MEIOSIS, continued...
As we’ll see, meiosis does something else that gets at the heart of
why sex is such a big hit, why it’s so popular from a biological
standpoint.
Why it was so crucial in the success of eukaryotes.
It produces lots of GENETIC DIVERSITY.
It shuffles genomes, providing new combinations of genes.
Why is that so important?
So how does meiosis work?
It consists of two different kinds of divisions.
Meiosis I and II.
The first division actually splits the chromosome pairs.
The second division is just a kind of mitotic division, but now
only one set of chromosomes is undergoing mitosis.
In prophase of meiosis I, chromosomes begin to coil up and shorten,
as in mitosis.
But they associate in HOMOLOGOUS pairs.
That is, e.g., both chromosome 2's pair up, both chromosome 17's, etc.
Since each chromosome has replicated, there are
FOUR chromatids in each pair.
By Metaphase I, the pairs line up on the metaphase plate.
Unlike mitosis, PAIRS line up side by side
on the plate. (Fig.
12.2)
However, they do NOT line up as maternal and paternal sets,
each set on one side of the plate.
Instead, maternal and paternal chromosomes are SCRAMBLED.
On either side of the metaphase plate, there is a mix
of maternal and
paternal chromosomes.
This is
IMPORTANT! See below....
In Anaphase I, the pairs separate towards opposite poles.
When daughter nuclei reform, each nucleus now contains
One set of chromosomes, but from mixed maternal and
paternal
origin.
(Note: this happens each generation!!)
At some point, often very quickly thereafter, another division
ensues.
Chomosomes condense, and eventually line up single file on
metaphase plate, a la mitosis.
Sister chromatid kinetochores now face in opposite directions,
as in mitosis.
By telophase, nuclei reform, and each one has one set of new
chromosomes
and becomes a sperm or an egg, depending on the
organ in which meiosis is occurring.
E.g. pollen vs ovary.
That’s how we reduce the chromosome number by half.
What about genetic diversity?
Remember, maternal and paternal sets are shuffled in metaphase.
Many possible combinations of chromosomes can result in each
sperm or egg?
Another souce of diversity: genetic recombination, or
CROSSING OVER.
During prophase I, when homologs pair, adjacent chromatids
exchange segments. (Figs. 12.2, 12.3, 12.5).
ALTERNATION OF GENERATIONS.
Figs. 12.1, 12.6
Mieosis is also important viz. when it occurs during an organism's
life cycle.
Two distinct phases or generations in life cycle
of a plant
One haploid (N), called the gametophyte
(gamete
bearing plant)
The other, diploid (2N), called the sporophyte
(spore bearing plant)
In algae, the group from which land plants emerged, haploid
generation is dominant.
Diploid phase very brief and reduced; just fertilized egg or ZYGOTE,
which then undergoes meiosis to produce 4 haploid spores.
I.e., meiosis is said to be ZYGOTIC.